SCHEMBL29587734

SCHEMBL29587734

O=C(O)C1CCc2ccc(OCc3ccc(Cl)cc3)cc2O1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 6/20 0.59
CYP4A11 Q02928 6/20 0.59
PPARG P37231 4/20 0.56
PPARA Q07869 4/20 0.56
PPARD Q03181 3/20 0.56
MAOB P27338 4/20 0.54
MAOA P21397 3/20 0.50
HTR6 P50406 1/20 0.48
NR4A2 P43354 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29052801 0.90 HTR6 (0.58) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL29586750 0.89 CYP4F2 (0.56) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL29586759 0.89 CYP4F2 (0.56) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL29587246 0.88 MAOB (0.48) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL29587114 0.86 CYP4F2 (0.56) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL431776 0.81 PPARG (0.58) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL29586849 0.81 CYP4F2 (0.53) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL10825353 0.80 PPARG (0.48) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL30982134 0.79 CYP4F2 (0.54) CYP4F2CYP4A11PPARGPPARAPPARD
SCHEMBL26105388 0.79 MAOB (0.50) MAOBMAOANR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022120048-A1 HDAC INHIBITORS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-06-09 WO disclosed