Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18617449 | 1.00 | CA3 (0.40) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL18617452 | 0.90 | ESR1 (0.40) | ESR1ESR2CNR1CNR2CYP11B2 | |
| SCHEMBL29588509 | 0.90 | ESR1 (0.40) | ESR1ESR2CNR1CNR2CYP11B2 | |
| SCHEMBL29588030 | 0.83 | CYP11B2 (0.41) | ESR1ESR2CNR1CNR2CYP11B2 | |
| SCHEMBL18617406 | 0.83 | CYP11B2 (0.41) | ESR1ESR2CNR1CNR2CYP11B2 | |
| SCHEMBL18618164 | 0.82 | BIRC5 (0.45) | CNR1 | |
| SCHEMBL29587650 | 0.82 | BIRC5 (0.45) | CNR1 | |
| SCHEMBL18617407 | 0.81 | CNR1 (0.47) | ESR1ESR2CNR1CNR2CYP11B2 | |
| SCHEMBL29587648 | 0.79 | FFAR4 (0.39) | CNR1CNR2 | |
| SCHEMBL18587952 | 0.79 | FFAR4 (0.39) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | HOFFMANN-LA ROCHE INC. (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | CNKSR1, RB1, RCOR1 | CA3 4316/4885CA6 1273/4885CA5A 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.