Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 4/20 | 0.31 |
| ▸ | KCNK10 | P57789 | 3/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | HNF4A | P41235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24393968 | 1.00 | PDE2A (0.37) | PDE2AALDH1A1LMNAKCNK2KCNK10 | |
| SCHEMBL29588039 | 0.84 | NR4A1 (0.40) | PDE2AALDH1A1 | |
| SCHEMBL24394138 | 0.84 | NR4A1 (0.40) | PDE2AALDH1A1 | |
| SCHEMBL26941570 | 0.81 | L3MBTL1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL24393967 | 0.74 | PDE2A (0.37) | PDE2AALDH1A1LMNAKCNK2KCNK10 | |
| SCHEMBL24394123 | 0.74 | CCR2 (0.32) | — | |
| SCHEMBL29588392 | 0.74 | CCR2 (0.32) | — | |
| SCHEMBL29588742 | 0.70 | PDE2A (0.38) | PDE2ALMNAKCNK2KCNK10TRPV1 | |
| SCHEMBL26929235 | 0.68 | PDE2A (0.36) | PDE2AALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL25043524 | 0.68 | NR4A1 (0.46) | PDE2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237408-A1 | ITACONIC ACID DERIVATIVES | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090723-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |