SCHEMBL295884

SCHEMBL295884

C=CC(=O)NCC(C(C)=O)C(C)=O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
TGM2 P21980 3/20 0.39
CYP2C19 P33261 1/20 0.32
GAA P10253 1/20 0.31
F13A1 P00488 1/20 0.31
LMNA P02545 1/20 0.31
TGM1 P22735 1/20 0.31
TGM3 Q08188 1/20 0.31
GFPT1 Q06210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28554680 0.83 TSHR (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL26907957 0.82 TSHR (0.38) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL9247246 0.79 MDM2 (0.42) TSHRALDH1A1TGM2CYP2C19LMNA
SCHEMBL372689 0.77
SCHEMBL18755013 0.77 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL5430601 0.77 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL12723737 0.77 TSHR (0.59) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL7744606 0.76 TSHR (0.52) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL10350868 0.76
SCHEMBL14901 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1682586-B1 AQUEOUS DISPERSIONS CONTAINING MULTI-STAGE EMULSION POLYMERS MOMENTIVE SPECIALTY CHEMICALS RES BELGIUM (BE) 2012-03-14 EP claimed
EP-1518846-B1 Moulded concrete article having high gloss, method of making the same and use thereof CELANESE EMULSIONS GMBH (DE) 2007-04-18 EP claimed
EP-1147139-B1 AQUEOUS COPOLYMER DISPERSION, ITS METHOD OF PRODUCTION AND ITS USE CELANESE EMULSIONS GMBH (DE) 2006-09-06 EP claimed
JP-2019351-A None JP disclosed
US-12486419-B2 Fluid set for inkjet recording AGFA NV (BE) 2025-12-02 US disclosed
EP-4570844-A1 NOVEL POLYTHIOPHENE/POLYANION COMPLEXES AGFA-GEVAERT NV (BE) 2025-06-18 EP disclosed
US-20240384121-A1 Fluid Set for Inkjet Recording AGFA NV (BE) 2024-11-21 US disclosed
EP-4284882-A1 FLUID SET FOR INKJET RECORDING AGFA NV (BE) 2023-12-06 EP disclosed
CN-116802239-A Fluid set for inkjet recording 爱克发有限公司 2023-09-22 CN disclosed
WO-2022161799-A1 FLUID SET FOR INKJET RECORDING AGFA NV (BE) 2022-08-04 WO disclosed
EP-1147139-A1 AQUEOUS COPOLYMER DISPERSION, ITS METHOD OF PRODUCTION AND ITS USE Clariant GmbH (DE) 2001-10-24 EP disclosed
WO-2000037516-A1 AQUEOUS COPOLYMER DISPERSION, ITS METHOD OF PRODUCTION AND ITS USE CLARIANT GMBH (DE) 2000-06-29 WO disclosed
EP-0345573-B1 2-[(Meth)acrylamidomethyl]-1,3-diketones BASF Aktiengesellschaft (DE) 1993-04-21 EP disclosed
US-5015768-A Reaction of diketone with methylol(meth)acrylamide by dehydration BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
US-5011991-A 2-((meth)acrylamidomethyl)-1,3-diketones BASF AKTIENGESELLSCHAFT (DE) 1991-04-30 US disclosed
JP-H0219351-A 2-((METH)ACRYLAMIDOMETHYL)-1,3-DIKETONE BASF AG 1990-01-23 JP disclosed
EP-0345573-A2 2-[(Meth)acrylamidomethyl]-1,3-diketones BASF Aktiengesellschaft (DE) 1989-12-13 EP disclosed