SCHEMBL9247246

SCHEMBL9247246

C=CC(=O)NCC(C(C)=O)C(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.42
KMT2A Q03164 1/20 0.42
TGM2 P21980 3/20 0.40
AKT1 P31749 1/20 0.40
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MTNR1A P48039 3/20 0.39
MTNR1B P49286 3/20 0.39
LMNA P02545 2/20 0.38
HPGD P15428 1/20 0.37
PGR P06401 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
HTR2A P28223 1/20 0.36
HRH1 P35367 1/20 0.36
KCNH2 Q12809 1/20 0.36
CTNNB1 P35222 1/20 0.36
GSTO1 P78417 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408489 0.91 MDM2 (0.47) MDM2KMT2ATGM2AKT1ALDH1A1
SCHEMBL9248562 0.91 MDM2 (0.47) MDM2KMT2ATGM2AKT1ALDH1A1
SCHEMBL9357443 0.89 MDM2 (0.46) MDM2KMT2ATGM2AKT1ALDH1A1
SCHEMBL9353340 0.83 NPC1 (0.43) MDM2KMT2ATGM2ALDH1A1GSTO1
SCHEMBL9242900 0.81 MDM2 (0.44) MDM2KMT2AALDH1A1CYP3A4MTNR1A
SCHEMBL28257710 0.79 TGM2 (0.42) MDM2KMT2ATGM2AKT1ALDH1A1
SCHEMBL295884 0.79 TSHR (0.50) TGM2ALDH1A1CYP2C19LMNATSHR
SCHEMBL10519219 0.78 TGM2 (0.41) MDM2KMT2ATGM2AKT1ALDH1A1
SCHEMBL6834266 0.76 MDM2 (0.49) MDM2KMT2AAKT1ALDH1A1CYP3A4
SCHEMBL9247552 0.74 MDM2 (0.46) MDM2KMT2AALDH1A1CYP3A4MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492210-B1 Polymer-coated concrete BASF AG (DE) 1994-09-21 EP claimed
US-5215827-A Acrylic amide or ester copolymers BASF AKTIENGESELLSCHAFT (DE) 1993-06-01 US claimed
EP-0492210-A1 Polymer-coated concrete BASF Aktiengesellschaft (DE) 1992-07-01 EP claimed
EP-4284882-A1 FLUID SET FOR INKJET RECORDING AGFA NV (BE) 2023-12-06 EP disclosed
EP-4277957-A1 FLUID SET FOR INKJET PRINTING AGFA NV (BE) 2023-11-22 EP disclosed
CN-116802239-A Fluid set for inkjet recording 爱克发有限公司 2023-09-22 CN disclosed
CN-116761859-A Fluid set for inkjet printing 爱克发有限公司 2023-09-15 CN disclosed
WO-2022161799-A1 FLUID SET FOR INKJET RECORDING AGFA NV (BE) 2022-08-04 WO disclosed
WO-2022152639-A1 FLUID SET FOR INKJET PRINTING AGFA NV (BE) 2022-07-21 WO disclosed
EP-0497101-B1 Fibre-based moulding compound BASF AG (DE) 1995-09-06 EP disclosed
EP-0492210-B1 Polymer-coated concrete BASF AG (DE) 1994-09-21 EP disclosed
EP-0497101-A2 Fibre-based moulding compound BASF Aktiengesellschaft (DE) 1992-08-05 EP disclosed
EP-0492210-A1 Polymer-coated concrete BASF Aktiengesellschaft (DE) 1992-07-01 EP disclosed
US-5015768-A Reaction of diketone with methylol(meth)acrylamide by dehydration BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
US-5011991-A 2-((meth)acrylamidomethyl)-1,3-diketones BASF AKTIENGESELLSCHAFT (DE) 1991-04-30 US disclosed
US-4946917-A 4-[(meth)acrylamidomethyl]-pyrazoles and -isoxazoles, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1990-08-07 US disclosed
US-4939268-A 4-(meth)acrylamidomethyl)-pyrazoles and -isoxazoles, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1990-07-03 US disclosed
EP-0345638-A1 4-[(Meth)acrylamidomethyl] pyrazoles and isoxazoles, process for their preparation and their use BASF Aktiengesellschaft (DE) 1989-12-13 EP disclosed
EP-0345573-A2 2-[(Meth)acrylamidomethyl]-1,3-diketones BASF Aktiengesellschaft (DE) 1989-12-13 EP disclosed
EP-0345636-A2 Light-sensitive negative lithographic printing plates BASF Aktiengesellschaft (DE) 1989-12-13 EP disclosed