Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313753 | 0.89 | MEN1 (0.38) | KAT6AFABP4 | |
| SCHEMBL24313699 | 0.87 | SCN9A (0.35) | KAT6AFABP4FABP5SCN9A | |
| SCHEMBL29587622 | 0.87 | SCN9A (0.35) | KAT6AFABP4FABP5SCN9A | |
| SCHEMBL24313965 | 0.86 | LMNA (0.38) | KAT6AFABP4FABP5SCN9AAR | |
| SCHEMBL22588224 | 0.85 | SCN9A (0.38) | KAT6AFABP4FABP5SCN9AHRH1 | |
| SCHEMBL24334278 | 0.84 | HRH1 (0.35) | KAT6AFABP4FABP5SCN9AHRH1 | |
| SCHEMBL29469716 | 0.84 | HRH1 (0.35) | KAT6AFABP4FABP5SCN9AHRH1 | |
| SCHEMBL29587885 | 0.84 | TRPV1 (0.35) | FABP4FABP5SCN9AP2RX4 | |
| SCHEMBL24313960 | 0.84 | TRPV1 (0.35) | FABP4FABP5SCN9AP2RX4 | |
| SCHEMBL31723099 | 0.83 | PTGER4 (0.36) | KAT6ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229045-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute Inc. (US) | 2023-08-23 | — | — | EP | claimed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | claimed |
| EP-4229045-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |