Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.70 |
| ▸ | NOS1 | P29475 | 3/20 | 0.70 |
| ▸ | NOS2 | P35228 | 3/20 | 0.70 |
| ▸ | SLC7A5 | Q01650 | 8/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288850 | 1.00 | NOS3 (0.70) | NOS3NOS1NOS2SLC7A5PTGS1 | |
| SCHEMBL287831 | 1.00 | NOS3 (0.70) | NOS3NOS1NOS2SLC7A5PTGS1 | |
| SCHEMBL7260682 | 1.00 | NOS3 (0.70) | NOS3NOS1NOS2SLC7A5PTGS1 | |
| SCHEMBL20715034 | 0.89 | NOS3 (0.59) | NOS3NOS1NOS2SLC7A5GRIA2 | |
| SCHEMBL6046229 | 0.87 | NOS3 (0.71) | NOS3NOS1NOS2SLC7A5PTGS1 | |
| SCHEMBL4629196 | 0.86 | NOS3 (0.53) | NOS3NOS1NOS2SLC7A5PTGS1 | |
| SCHEMBL3152192 | 0.85 | NOS3 (0.73) | NOS3NOS1NOS2SLC7A5PTGS1 | |
| SCHEMBL20502934 | 0.85 | NOS3 (0.73) | NOS3NOS1NOS2SLC7A5PTGS1 | |
| SCHEMBL20502933 | 0.85 | NOS3 (0.73) | NOS3NOS1NOS2SLC7A5PTGS1 | |
| SCHEMBL8075751 | 0.83 | NOS3 (0.50) | NOS3NOS1NOS2CASRITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981784-A1 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2022-04-13 | — | — | EP | disclosed |