Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29590775 | 0.93 | HSP90AA1 (0.47) | NAMPTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL29590949 | 0.88 | NAMPT (0.42) | OPRM1OPRD1OPRK1NAMPTMCL1 | |
| SCHEMBL29589684 | 0.86 | BCL2 (0.51) | OPRM1OPRD1OPRK1NAMPTHSP90B1 | |
| SCHEMBL16416972 | 0.84 | HSP90AA1 (0.47) | NAMPTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL29589723 | 0.84 | BCL2 (0.52) | CTSDBCL2 | |
| SCHEMBL29589765 | 0.84 | BCL2 (0.49) | NAMPTHSP90B1BCL2HSP90AA1HSP90AB1 | |
| SCHEMBL29590466 | 0.84 | HSP90AA1 (0.47) | NAMPTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL29589757 | 0.83 | BCL2 (0.42) | NAMPTMCL1CTSDHSP90B1BCL2 | |
| SCHEMBL29589890 | 0.83 | NAMPT (0.59) | NAMPTBCL2LMNAPKM | |
| SCHEMBL29591015 | 0.82 | BCL2 (0.53) | BCL2BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |