Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29590211 | 0.94 | RAB9A (0.62) | NAMPTRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL29589684 | 0.88 | BCL2 (0.51) | NAMPTBCL2LMNAPKM | |
| SCHEMBL29587968 | 0.88 | NAMPT (0.57) | NAMPTBCL2 | |
| SCHEMBL29590949 | 0.83 | NAMPT (0.42) | NAMPTBCL2LMNAPKM | |
| SCHEMBL29589831 | 0.83 | OPRM1 (0.43) | NAMPTBCL2LMNAPKM | |
| SCHEMBL28278989 | 0.82 | NPC1 (0.56) | NAMPTRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL29591192 | 0.82 | BCL2 (0.51) | NAMPTRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL29589723 | 0.81 | BCL2 (0.52) | BCL2 | |
| SCHEMBL23327023 | 0.81 | NPC1 (0.55) | NAMPTRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL29590775 | 0.79 | HSP90AA1 (0.47) | NAMPTSMN1; SMN2NPC1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |