SCHEMBL29591122

SCHEMBL29591122

CCCCCCCCC1(CCCCCCCC)c2cc(Cl)ccc2-c2ccc(Br)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.34
ABL1 P00519 1/20 0.32
HTR7 P34969 1/20 0.32
CCR5 P51681 2/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MMP2 P08253 2/20 0.31
MMP9 P14780 2/20 0.31
MMP8 P22894 2/20 0.31
MMP13 P45452 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.31
AKR1A1 P14550 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL198215 1.00 PDK2 (0.34) PDK2ABL1HTR7CCR5NPC1
SCHEMBL29591416 1.00 PDK2 (0.34) PDK2ABL1HTR7CCR5NPC1
SCHEMBL196978 1.00 PDK2 (0.34) PDK2ABL1HTR7CCR5NPC1
SCHEMBL196788 1.00 PDK2 (0.34) PDK2ABL1HTR7CCR5NPC1
SCHEMBL811806 1.00 PDK2 (0.34) PDK2ABL1HTR7CCR5NPC1
SCHEMBL15674381 0.99 PDK2 (0.33) PDK2ABL1HTR7CCR5NPC1
SCHEMBL26050359 0.97 PDK2 (0.33) PDK2ABL1HTR7CCR5NPC1
SCHEMBL197894 0.91 LMNA (0.36) PDK2NPC1GAANFKB1RAB9A
SCHEMBL196478 0.91 PDK2 (0.40) PDK2HTR7GAASMN1; SMN2MMP2
SCHEMBL196824 0.91 PDK2 (0.40) PDK2HTR7GAASMN1; SMN2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003271-B Process for producing aromatic compound 住友化学株式会社 2022-05-03 CN disclosed