SCHEMBL29591887

SCHEMBL29591887

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 6/20 0.47
▸ SLC6A2 P23975 1/20 0.45
▸ CAPN1 P07384 6/20 0.45
▸ CTSB P07858 3/20 0.44
▸ NTSR2 O95665 2/20 0.42
▸ NTSR1 P30989 2/20 0.42
▸ ANPEP P15144 1/20 0.42
▸ LNPEP Q9UIQ6 1/20 0.42
▸ CTSD P07339 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29845324 0.95 REN (0.46) RENSLC6A2NTSR2NTSR1
SCHEMBL30385689 0.94 REN (0.47) RENSLC6A2NTSR2NTSR1CTSD
SCHEMBL29630596 0.92 MEN1 (0.43) RENCAPN1CTSB
SCHEMBL30997440 0.91 REN (0.45) RENSLC6A2CAPN1CTSBANPEP
SCHEMBL30997442 0.91 REN (0.45) RENSLC6A2CAPN1CTSBANPEP
SCHEMBL31072130 0.89 REN (0.46) RENNTSR2NTSR1
SCHEMBL29591934 0.87 GRB2 (0.43) SLC6A2
SCHEMBL29590547 0.87 OPRK1 (0.46) RENSLC6A2CTSD
SCHEMBL11092435 0.87 REN (0.47) RENSLC6A2NTSR2NTSR1
SCHEMBL29630560 0.87 OPRK1 (0.46) RENSLC6A2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618102-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited (GB) 2026-05-05 — — US disclosed
US-20220112547-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618102-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions POLM, POLR1A, POLR1E REN 1530/4885SLC6A2 2983/4885CAPN1 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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