Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.57 |
| ▸ | PAK4 | O96013 | 1/20 | 0.51 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592844 | 0.85 | IGF1R (0.53) | IGF1R | |
| SCHEMBL6828271 | 0.79 | CDK7 (0.44) | — | |
| SCHEMBL29592988 | 0.74 | PAK4 (0.37) | IGF1RPAK4PAK1 | |
| SCHEMBL30595312 | 0.73 | IGF1R (0.53) | IGF1R | |
| SCHEMBL26273491 | 0.72 | NEK1 (0.72) | IGF1RPAK4PAK1 | |
| SCHEMBL15109539 | 0.70 | IGF1R (0.78) | IGF1R | |
| SCHEMBL31471722 | 0.70 | ULK1 (0.72) | IGF1RPAK4PAK1 | |
| SCHEMBL15209365 | 0.70 | IGF1R (0.50) | IGF1R | |
| SCHEMBL24174420 | 0.70 | PAK4 (0.57) | IGF1RPAK4PAK1 | |
| SCHEMBL12845807 | 0.70 | IGF1R (0.58) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204411-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | Nalo Therapeutics (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022046861-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2022-03-03 | — | — | WO | disclosed |