Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 7/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316452 | 0.92 | BACE1 (0.49) | MMEFOLH1TASP1GRIN2DGRIN3B | |
| SCHEMBL5316454 | 0.92 | BACE1 (0.49) | MMEFOLH1TASP1GRIN2DGRIN3B | |
| SCHEMBL29660983 | 0.92 | GRIN2D (0.45) | MMEFOLH1TASP1GRIN2DGRIN3B | |
| SCHEMBL30381819 | 0.91 | FOLH1 (0.56) | MMEFOLH1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL30296770 | 0.90 | NMT1 (0.53) | MMEFOLH1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29624868 | 0.89 | MME (0.56) | MMEFOLH1 | |
| SCHEMBL29531331 | 0.89 | FOLH1 (0.61) | MMEFOLH1 | |
| SCHEMBL29419017 | 0.89 | FOLH1 (0.61) | MMEFOLH1 | |
| SCHEMBL5310633 | 0.87 | KEAP1 (0.46) | MMETASP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5310645 | 0.87 | KEAP1 (0.46) | MMETASP1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549143-B | Anti-tumor polypeptide Bax-BH3, fluorescent polymer nano micelle and preparation method and application thereof | 吉林大学 | 2022-05-27 | — | — | CN | disclosed |