Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29593455 | 1.00 | HSD17B10 (0.40) | HSD17B10GPR119KMT2ALMNANPSR1 | |
| SCHEMBL31286151 | 0.87 | GPR119 (0.37) | HSD17B10GPR119KMT2ALMNANPSR1 | |
| SCHEMBL22142845 | 0.84 | GPR119 (0.39) | HSD17B10GPR119LMNANPSR1SMN1; SMN2 | |
| SCHEMBL22142936 | 0.84 | GPR119 (0.39) | HSD17B10GPR119LMNANPSR1SMN1; SMN2 | |
| SCHEMBL22142862 | 0.84 | GPR119 (0.39) | HSD17B10GPR119LMNANPSR1SMN1; SMN2 | |
| SCHEMBL29592649 | 0.83 | HSD17B10 (0.40) | HSD17B10GPR119KMT2ALMNANPSR1 | |
| SCHEMBL29929712 | 0.79 | MEN1 (0.43) | GPR119KMT2ALMNANPSR1NPC1 | |
| SCHEMBL11990563 | 0.75 | HSD17B10 (0.35) | HSD17B10GPR119LMNANPSR1NR1H2 | |
| SCHEMBL29929448 | 0.75 | ALDH1A1 (0.36) | HSD17B10KMT2ALMNANPSR1NPC1 | |
| SCHEMBL5420095 | 0.75 | HSD17B10 (0.42) | HSD17B10GPR119SMN1; SMN2ADORA1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591223-A | Beta-lactamase inhibitor compounds | 恩塔西斯治疗有限公司 | 2022-06-07 | — | — | CN | disclosed |