Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 12/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deracoxib SCHEMBL24645 | 1.00 | PTGS2 (1.00) | PTGS2PTGS1ABCB11ALDH1A1 | |
| Deracoxib SCHEMBL6601340 | 0.99 | PTGS2 (0.98) | PTGS2PTGS1ABCB11ALDH1A1 | |
| Deracoxib SCHEMBL28723602 | 0.99 | PTGS2 (0.98) | PTGS2PTGS1ABCB11ALDH1A1 | |
| Deracoxib SCHEMBL6599167 | 0.95 | PTGS2 (0.91) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL6343102 | 0.92 | PTGS2 (0.84) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL6341965 | 0.91 | PTGS2 (0.83) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL6349615 | 0.90 | PTGS2 (0.81) | PTGS2PTGS1ABCB11ALDH1A1 | |
| Deracoxib SCHEMBL6909431 | 0.89 | PTGS2 (0.80) | PTGS2PTGS1ABCB11ALDH1A1 | |
| Deracoxib SCHEMBL6598846 | 0.89 | PTGS2 (0.79) | PTGS2PTGS1ABCB11ALDH1A1 | |
| Deracoxib SCHEMBL6598844 | 0.89 | PTGS2 (0.79) | PTGS2PTGS1ABCB11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689633-B | For inhibiting Nav1.8 Pyridinecarboxamide Compounds | 利伯研究所公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-114874209-B | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-117940166-A | SOS1 inhibitors and RAS inhibitors for the treatment of pain | 塞文莱斯治疗有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-112689629-B | For inhibiting Nav1.8 Pyridazine Compounds | 利伯研究所公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-113853196-B | Long-acting injectable formulations and uses thereof | 皮埃蒙特动物健康公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117530943-A | Formulations for administration of efluromithine | 奥巴斯治疗股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116589465-A | Cyclic molecules as inhibitors of bruton's tyrosine kinase | 明慧医药（上海）有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116437930-A | Use of uridine derivatives in the preparation of medicaments | 上海岸阔医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116367842-A | Application of thymidine derivative in preparing medicine | 上海岸阔医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-109789144-B | Protein kinase modulators | 马德拉医疗公司 | 2022-04-15 | — | — | CN | disclosed |