Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29594807 | 0.86 | NPC1 (0.57) | POLBGLAMAPTHPGDL3MBTL1 | |
| SCHEMBL29594778 | 0.86 | NPC1 (0.57) | POLBGLASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL29593773 | 0.86 | MAPT (0.59) | POLBGLASMN1; SMN2MAPTHPGD | |
| SCHEMBL29594256 | 0.84 | TP53 (0.55) | POLBGLASMN1; SMN2MAPTHPGD | |
| SCHEMBL29593974 | 0.81 | ALDH1A1 (0.48) | POLBGLASMN1; SMN2MAPTHPGD | |
| SCHEMBL29594581 | 0.78 | NPC1 (0.55) | POLBGLASMN1; SMN2MAPTHPGD | |
| SCHEMBL5024162 | 0.73 | POLB (0.58) | POLBGLASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL852214 | 0.72 | POLB (0.57) | POLBGLASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9464873 | 0.72 | POLB (0.57) | POLBGLASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL30264508 | 0.72 | POLB (0.57) | POLBGLASMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003080-B | Selenium-containing compound and preparation method and application thereof | 成都大学 | 2022-05-06 | — | — | CN | disclosed |