SCHEMBL295940

SCHEMBL295940

NNc1c(Cl)c(Cl)nc(C(=O)O)c1Cl

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
NOX1 Q9Y5S8 1/20 0.49
KDM4E B2RXH2 4/20 0.46
GAA P10253 1/20 0.46
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HCAR2 Q8TDS4 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
PTPRB P23467 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPT P10636 2/20 0.30
KDM5A P29375 1/20 0.30
JMJD1C Q15652 1/20 0.30
KDM3A Q9Y4C1 1/20 0.30
ALDH1A1 P00352 1/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397972 0.76 KDM4E (0.61) KDM4EGAA
SCHEMBL3257142 0.74 TDP1 (0.65) TDP1NOX1KDM4EGAAMEN1
SCHEMBL29688221 0.74 TDP1 (0.65) TDP1NOX1KDM4EGAAMEN1
Picloram SCHEMBL29388079 0.74 TDP1 (1.00) TDP1NOX1KDM4EGAAMEN1
Picloram SCHEMBL13299 0.74 TDP1 (1.00) TDP1NOX1KDM4EGAAMEN1
Picloram SCHEMBL8467014 0.74 TDP1 (1.00) TDP1NOX1KDM4EGAAMEN1
Picloram SCHEMBL15437675 0.72 TDP1 (0.96) TDP1NOX1KDM4EGAAMEN1
Picloram SCHEMBL7112378 0.72 TDP1 (0.96) TDP1NOX1KDM4EGAAMEN1
Picloram SCHEMBL28547325 0.72 TDP1 (0.96) TDP1NOX1KDM4EGAAMEN1
Picloram SCHEMBL29705200 0.72 TDP1 (0.96) TDP1NOX1KDM4EGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4087431-A Preparation of 3,6-dichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1978-05-02 US claimed
US-3971799-A Preparation of 3,5,6-trichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1976-07-27 US claimed
EP-2331649-B1 METHODS AND COMPOSITIONS FOR POLISHING SILICON-CONTAINING SUBSTRATES CABOT MICROELECTRONICS CORP (US) 2018-06-13 EP disclosed
US-8597540-B2 Compositions for polishing silicon-containing substrates CABOT MICROELECTRONICS CORPORATION (US) 2013-12-03 US disclosed
US-20130200039-A1 AQUEOUS POLISHING COMPOSITIONS CONTAINING N-SUBSTITUTED DIAZENIUM DIOXIDES AND/OR N'-HYDROXY-DIAZENIUM OXIDE SALTS BASF SE (DE) 2013-08-08 US disclosed
EP-2614122-A1 AQUEOUS POLISHING COMPOSITIONS CONTAINING N-SUBSTITUTED DIAZENIUM DIOXIDES AND/OR N'-HYDROXY-DIAZENIUM OXIDE SALTS BASF SE (DE) 2013-07-17 EP disclosed
US-8486169-B2 Method of polishing a silicon-containing dielectric CABOT MICROELECTRONICS CORPORATION (US) 2013-07-16 US disclosed
US-20130168348-A1 AQUEOUS POLISHING COMPOSITION AND PROCESS FOR CHEMICALLY MECHANICALLY POLISHING SUBSTRATES CONTAINING SILICON OXIDE DIELECTRIC AND POLYSILICON FILMS BASF SE (DE) 2013-07-04 US disclosed
US-20130171824-A1 PROCESS FOR CHEMICALLY MECHANICALLY POLISHING SUBSTRATES CONTAINING SILICON OXIDE DIELECTRIC FILMS AND POLYSILICON AND/OR SILICON NITRIDE FILMS BASF SE (DE) 2013-07-04 US disclosed
US-20120280170-A1 COMPOSITIONS FOR POLISHING SILICON-CONTAINING SUBSTRATES CABOT MICROELECTRONICS CORPORATION 2012-11-08 US disclosed
US-8247327-B2 Methods and compositions for polishing silicon-containing substrates CABOT MICROELECTRONICS CORPORATION (US) 2012-08-21 US disclosed
EP-1601735-A1 METHOD OF POLISHING A SILICON-CONTAINING DIELECTRIC Cabot Microelectronics Corporation (US) 2005-12-07 EP disclosed
WO-2004069947-A1 METHOD OF POLISHING A SILICON-CONTAINING DIELECTRIC CABOT MICROELECTRONICS CORPORATION (US) 2004-08-19 WO disclosed
US-20040152309-A1 Method of polishing a silicon-containing dielectric CABOT MICROELECTRONICS CORPORATION 2004-08-05 US disclosed
US-4594422-A Hydroxylation of a 6-halo picolinic acid with a aqueous mineral acid solution; then halogenating THE DOW CHEMICAL COMPANY (US) 1986-06-10 US disclosed
US-4334074-A BY ACIDIFICATION WITH HYDROGEN CHLORIDE IN THE PRESENCE OF A FLOCCULANT THE DOW CHEMICAL COMPANY (US) 1982-06-08 US disclosed
US-4087431-A Preparation of 3,6-dichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1978-05-02 US disclosed
US-4087431-A Preparation of 3,6-dichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1978-05-02 US disclosed
US-3971799-A Preparation of 3,5,6-trichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1976-07-27 US disclosed
US-3971799-A Preparation of 3,5,6-trichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1976-07-27 US disclosed