Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27511732 | 0.86 | ATM (0.61) | HCAR2ATMKEAP1NFE2L2NPSR1 | |
| SCHEMBL9579502 | 0.82 | HCAR2 (0.56) | HCAR2ATMNPSR1MAPTRAB9A | |
| SCHEMBL3181990 | 0.81 | — | — | |
| SCHEMBL29386852 | 0.81 | TSHR (0.52) | HCAR2ATMHPGDTSHRALDH1A1 | |
| SCHEMBL7096990 | 0.79 | ALDH1A1 (0.45) | HCAR2ATMKEAP1NFE2L2NPSR1 | |
| SCHEMBL7098799 | 0.79 | ALDH1A1 (0.45) | HCAR2ATMKEAP1NFE2L2NPSR1 | |
| SCHEMBL28321465 | 0.79 | HCAR2 (0.46) | HCAR2ATMKEAP1NFE2L2NPSR1 | |
| SCHEMBL28250454 | 0.79 | HCAR2 (0.46) | HCAR2ATMKEAP1NFE2L2NPSR1 | |
| SCHEMBL692723 | 0.79 | HCAR2 (0.67) | HCAR2ATMNPSR1MAPTRAB9A | |
| SCHEMBL692722 | 0.79 | HCAR2 (0.67) | HCAR2ATMNPSR1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502174-A | 2,4,7 substituted-7-deaza-2 '-deoxy-2' -fluoroarabinosucleosides and nucleotide prodrugs and use thereof | 南方研究院 | 2022-05-13 | — | — | CN | disclosed |