SCHEMBL7098799

SCHEMBL7098799

CCOCCOOC(=O)/C=C/C(=O)OOCCOCC

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
THRB P10828 2/20 0.44
HCAR2 Q8TDS4 6/20 0.39
ATM Q13315 1/20 0.39
NPSR1 Q6W5P4 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31
RAB9A P51151 2/20 0.30
NPC1 O15118 1/20 0.30
HPGD P15428 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096990 1.00 ALDH1A1 (0.45) ALDH1A1TSHRTHRBHCAR2ATM
SCHEMBL9729214 0.83 TSHR (0.47) ALDH1A1TSHRTHRBTP53HIF1A
SCHEMBL29595192 0.79 HCAR2 (0.50) ALDH1A1TSHRHCAR2ATMNPSR1
SCHEMBL28250454 0.79 HCAR2 (0.46) ALDH1A1HCAR2ATMNPSR1KEAP1
SCHEMBL28321465 0.79 HCAR2 (0.46) ALDH1A1HCAR2ATMNPSR1KEAP1
SCHEMBL9062712 0.77 ALDH1A1 (0.60) ALDH1A1TSHRTHRBHSD17B10RAB9A
SCHEMBL2897724 0.77 ALDH1A1 (0.60) ALDH1A1TSHRTHRBHCAR2ATM
SCHEMBL2898088 0.77 ALDH1A1 (0.60) ALDH1A1TSHRTHRBHCAR2ATM
SCHEMBL2962177 0.76 ALDH1A1 (0.58) ALDH1A1TSHRTHRBHCAR2ATM
SCHEMBL5182220 0.76 ALDH1A1 (0.58) ALDH1A1TSHRTHRBHCAR2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1339127-A1 SOLID POLYMER ELECTROLYTE AND CELL CONTAINING THE ELECTROLYTE DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-08-27 EP disclosed