Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249695 | 1.00 | MAPT (0.52) | MAPTCYP3A4PTGS2PTGS1HTR6 | |
| SCHEMBL19212556 | 0.83 | PTGS2 (0.46) | MAPTPTGS2PTGS1HTR6ALDH1A1 | |
| SCHEMBL29596224 | 0.79 | NPC1 (0.49) | MAPTPTGS2PTGS1HTR6KDM4E | |
| SCHEMBL19212565 | 0.79 | NPC1 (0.49) | MAPTPTGS2PTGS1HTR6KDM4E | |
| SCHEMBL6920607 | 0.78 | MAPT (0.61) | MAPTCYP3A4HTR6KDM4EHSD17B10 | |
| SCHEMBL29595705 | 0.77 | PTPN5 (0.56) | MAPTPTGS2PTGS1KDM4EHSD17B10 | |
| SCHEMBL19249951 | 0.77 | PTPN5 (0.56) | MAPTPTGS2PTGS1KDM4EHSD17B10 | |
| SCHEMBL3078541 | 0.77 | HTT (0.57) | MAPTCYP3A4PTGS2PTGS1HTR6 | |
| SCHEMBL4443613 | 0.76 | MAPT (0.51) | MAPTCYP3A4PTGS2PTGS1HTR6 | |
| SCHEMBL693485 | 0.76 | PTGS1 (0.60) | MAPTCYP3A4PTGS2PTGS1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153642-B | Indole and azaindole halogenated allylamine derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2022-05-17 | — | — | CN | disclosed |