Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29380988 | 0.88 | PTGS1 (0.45) | PTGS1PTGS2ALDH1A1SKP2CNR1 | |
| SCHEMBL311370 | 0.88 | PTGS1 (0.45) | PTGS1PTGS2ALDH1A1SKP2CNR1 | |
| SCHEMBL29597103 | 0.88 | PTGS1 (0.45) | PTGS1PTGS2ALDH1A1SKP2CNR1 | |
| SCHEMBL21338804 | 0.86 | PTGS1 (0.37) | PTGS1PTGS2FFAR4FFAR1SKP2 | |
| SCHEMBL21096720 | 0.80 | TPMT (0.50) | FFAR4FFAR1ALDH1A1CNR1 | |
| SCHEMBL6480325 | 0.80 | GFER (0.61) | ALDH1A1SKP2 | |
| SCHEMBL3690305 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TAAR1CNR1RAPGEF4 | |
| SCHEMBL2551561 | 0.77 | MAOA (0.48) | PTGS1PTGS2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL13580008 | 0.77 | PTGS1 (0.42) | PTGS1PTGS2ALDH1A1SKP2CNR1 | |
| SCHEMBL8072351 | 0.77 | PTGS1 (0.39) | PTGS1PTGS2ALDH1A1SKP2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096680-A | REUSABLE ALUMINUM FRIEDEL-CRAFTS CATALYSTS; FORMED FROM AN ALUMINUM TRIHALIDE, ALKALI METAL HALIDE OR PSEUDOHALIDE, ALKALINE EARTH METAL HALIDE, QUATERNARY AMMONIUM, PHOSPHONIUM AND/OR SULFONIUM SALT AND AN AROMATIC HYDROCARBON | ALBEMARLE CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| WO-1999054038-A1 | LIQUID CLATHRATE COMPOSITIONS | ALBEMARLE CORPORATION (US) | 1999-10-28 | — | — | WO | disclosed |
| US-5859302-A | Processes employing reusable aluminum catalysts | ALBEMARLE CORPORATION (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0838447-A1 | Processes employing reusable aluminum catalysts | ALBEMARLE CORPORATION (US) | 1998-04-29 | — | — | EP | disclosed |