Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27188918 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2CA1CA2CA4CA7 | |
| SCHEMBL5403243 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2CA1CA2CA4CA7 | |
| SCHEMBL29713980 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2CA1CA2CA4CA7 | |
| SCHEMBL27188917 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2CA1CA2CA4CA7 | |
| SCHEMBL3958079 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2CA1CA2CA4CA7 | |
| SCHEMBL4950145 | 0.79 | SRD5A1 (0.43) | SMN1; SMN2METAP1ALDH1A1 | |
| SCHEMBL10341535 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2CA1CA2CA4CA7 | |
| SCHEMBL27188923 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2CA1CA2CA4CA7 | |
| SCHEMBL28910708 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2CA1CA2CA4CA7 | |
| SCHEMBL28547728 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013738-A1 | PROCESS FOR PREPARING 1-INDANONE COMPOUNDS BY INTRAMOLECULAR FRIEDEL-CRAFTS REACTION OF ALPHA,ALPHA-DIALKYLMALONATE DERIVATIVES | Firmenich SA (CH) | 2022-06-22 | — | — | EP | claimed |
| CN-114514219-A | Process for the preparation of 1-indanone compounds by intramolecular friedel-crafts reaction of derivatives of α, α -dialkyl malonates | 弗门尼舍有限公司 | 2022-05-17 | — | — | CN | claimed |
| EP-4013738-A1 | PROCESS FOR PREPARING 1-INDANONE COMPOUNDS BY INTRAMOLECULAR FRIEDEL-CRAFTS REACTION OF ALPHA,ALPHA-DIALKYLMALONATE DERIVATIVES | Firmenich SA (CH) | 2022-06-22 | — | — | EP | disclosed |
| CN-114514219-A | Process for the preparation of 1-indanone compounds by intramolecular friedel-crafts reaction of derivatives of α, α -dialkyl malonates | 弗门尼舍有限公司 | 2022-05-17 | — | — | CN | disclosed |