Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 4/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 6/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141221 | 0.84 | SMN1; SMN2 (0.53) | SRD5A1SRD5A2BACE1METAP1SMN1; SMN2 | |
| SCHEMBL5612010 | 0.82 | KDM4E (0.40) | METAP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2947059 | 0.81 | SRD5A1 (0.45) | SRD5A1SRD5A2BACE1HSP90AA1METAP1 | |
| SCHEMBL2941707 | 0.81 | SRD5A1 (0.45) | SRD5A1SRD5A2BACE1HSP90AA1METAP1 | |
| SCHEMBL27236999 | 0.80 | OPRM1 (0.41) | SMN1; SMN2HTR2AALDH1A1TP53HTR2B | |
| SCHEMBL29597471 | 0.79 | SMN1; SMN2 (0.61) | METAP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27188918 | 0.79 | SMN1; SMN2 (0.61) | METAP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29405349 | 0.79 | METAP1 (0.41) | SRD5A1SRD5A2BACE1METAP1DRD2 | |
| SCHEMBL29448019 | 0.78 | METAP1 (0.43) | SRD5A1SRD5A2METAP1DRD2HTR2A | |
| SCHEMBL14430319 | 0.78 | METAP1 (0.43) | SRD5A1SRD5A2METAP1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414157-B2 | Hydroxylation of β-dicarbonyls with zirconium catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
| US-7312335-B2 | Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts | BRANDEIS UNIVERSITY (US) | 2007-12-25 | — | — | US | disclosed |
| US-20060014956-A1 | Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts | BRANDEIS UNIVERSITY | 2006-01-19 | — | — | US | disclosed |
| EP-0567138-A2 | Hydrazone derivatives, process for producing the same, insecticides and/or acaricides containing the same as active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014956-A1 | Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts | ALDH3A1, NQO1, DERA | SRD5A1 737/4885SRD5A2 765/4885BACE1 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.