Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192085 | 1.00 | MPO (0.49) | MPOMAPK14LTA4HALOX5APCYP19A1 | |
| Bromide SCHEMBL29598384 | 0.98 | MPO (0.48) | MPOMAPK14LTA4HALOX5APCYP19A1 | |
| Bromide SCHEMBL22834597 | 0.98 | MPO (0.48) | MPOMAPK14LTA4HALOX5APCYP19A1 | |
| SCHEMBL10515095 | 0.85 | LTA4H (0.53) | MPOMAPK14LTA4HALOX5APCYP19A1 | |
| SCHEMBL16094138 | 0.81 | PLAU (0.45) | MAPK14LTA4HRAB9ASMN1; SMN2MAOB | |
| SCHEMBL16805009 | 0.81 | SMN1; SMN2 (0.47) | MAPK14LTA4HRAB9ASMN1; SMN2MAOB | |
| SCHEMBL10200181 | 0.81 | MAPT (0.50) | MAPK14LTA4HRAB9ASMN1; SMN2MAOB | |
| SCHEMBL31488465 | 0.81 | PLAU (0.45) | MAPK14LTA4HRAB9ASMN1; SMN2MAOB | |
| SCHEMBL25595344 | 0.81 | MPO (0.49) | MPOMAPK14LTA4HALOX5APCYP19A1 | |
| SCHEMBL16093908 | 0.80 | SMN1; SMN2 (0.42) | MAPK14LTA4HRAB9ASMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114245796-B | Imidazo [1,2-a ] pyridinyl derivatives and their use in the treatment of diseases | 比奥根MA公司 | 2024-07-30 | — | — | CN | disclosed |
| EP-3990454-A1 | IMIDAZO[1,2-A]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | Biogen MA Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-114245796-A | Imidazo [1,2-a ] pyridinyl derivatives and their use in the treatment of disease | 比奥根MA公司 | 2022-03-25 | — | — | CN | disclosed |