SCHEMBL295994

SCHEMBL295994

C1=C(CC(C2=CCCCCCCCCCC2)(C2=CCCCCCCCCCC2)C2=CCCCCCCCCCC2)CCCCCCCCCC1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CXCR3 P49682 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
ALOX15 P16050 2/20 0.36
ALDH1A1 P00352 4/20 0.35
NPC1 O15118 1/20 0.33
EPHX1 P07099 1/20 0.33
RAB9A P51151 1/20 0.33
USP2 O75604 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.32
PKM P14618 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL634874 0.75 TAAR1 (0.38) SMN1; SMN2ALDH1A1NPC1EPHX1RAB9A
SCHEMBL11134470 0.75 TAAR1 (0.38) SMN1; SMN2ALDH1A1NPC1EPHX1RAB9A
SCHEMBL153483 0.75 TAAR1 (0.38) SMN1; SMN2ALDH1A1NPC1EPHX1RAB9A
SCHEMBL28568464 0.75
SCHEMBL21319042 0.73 ALDH1A1 (0.33) ALOX15ALDH1A1NPC1RAB9A
SCHEMBL10917130 0.72 ALDH1A1 (0.42) CXCR3SMN1; SMN2ALOX15ALDH1A1NPC1
SCHEMBL4842355 0.72 ALDH1A1 (0.38) CXCR3SMN1; SMN2ALOX15ALDH1A1NPC1
SCHEMBL850818 0.71 KDM1A (0.33)
SCHEMBL2513477 0.71 ALDH1A1 (0.52) CXCR3SMN1; SMN2ALOX15ALDH1A1NPC1
SCHEMBL7593007 0.71 KDM1A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210213700-A1 PACKAGING FOR ADHESIVE COMPOSITIONS H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. 2021-07-15 US claimed
WO-2018148057-A1 PACKAGING FOR ADHESIVE COMPOSITIONS, METHOD FOR STERILIZING ADHEZION BIOMEDICAL, LLC (US) 2018-08-16 WO claimed
US-20180222618-A1 PACKAGING FOR ADHESIVE COMPOSITIONS H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. 2018-08-09 US claimed
WO-2012059403-A1 COSMETIC COMPOSITION AND PROCESS FOR CURLING KERATIN FIBRES L'OREAL (FR) 2012-05-10 WO claimed
EP-1372844-B1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2011-01-05 EP claimed
EP-1372844-A4 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2005-10-12 EP claimed
US-6838489-B2 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor CYMETECH, LLC (US) 2005-01-04 US claimed
EP-1372844-A1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR California Institute of Technology (US) 2004-01-02 EP claimed
WO-2003097562-A2 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-11-27 WO claimed
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor STERLING JA, L.C. 2003-07-31 US claimed
US-5468803-A Medical implement, polymer composition, and optical material NIPPON ZEON CO. LTD. (JP) 1995-11-21 US claimed
EP-0426142-B1 Method of making ring-opened polynorbornene polymers using pot life extending agents NIPPON ZEON CO (JP) 1995-09-20 EP claimed
US-5439992-A Continuous process for making melt-processable optical grade ring-opened polycyclic (co)polymers in a single-stage multi-zoned reactor THE B. F. GOODRICH COMPANY (US) 1995-08-08 US claimed
EP-0454059-B1 Composite molded articles NIPPON ZEON CO (JP) 1995-05-17 EP claimed
US-5204427-A Without prolonging smoke time; molybdenum metathesis catalyst and cocatalyst; bicyclic polyunsaturated extender NIPPON ZEON CO., LTD. (JP) 1993-04-20 US claimed
US-5160772-A COMPOSITE MOLDED ARTICLES NIPPON ZEON CO., LTD. (JP) 1992-11-03 US claimed
EP-0488135-A2 Bulk polymerizable reaction solutions NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP claimed
EP-0454059-A2 Composite molded articles NIPPON ZEON KABUSHIKI KAISHA (JP) 1991-10-30 EP claimed
EP-0426142-A2 Method of making ring-opened polynorbornene polymers using pot life extending agents NIPPON ZEON CO., LTD. (JP) 1991-05-08 EP claimed
US-4178424-A USED FOR AUTOMOTIVE PARTS THE BF GOODRICH COMPANY (US) 1979-12-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor NQO1, NIT2, ALOX5 CXCR3 2850/4885SMN1; SMN2 1687/4885ALOX15 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.