SCHEMBL29600028

SCHEMBL29600028

O=C(c1n[nH]c2c1CCN(CC1CC1)C2)N1CCC(c2cc(F)cc(F)c2C(F)(F)F)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17229641 1.00 RBP4 (1.00) RBP4
SCHEMBL17222920 0.93 RBP4 (0.88) RBP4
SCHEMBL29813075 0.93 RBP4 (0.88) RBP4
SCHEMBL17229901 0.91 RBP4 (1.00) RBP4
SCHEMBL17229642 0.91 RBP4 (0.84) RBP4
SCHEMBL17222973 0.88 RBP4 (1.00) RBP4
SCHEMBL29813277 0.88 RBP4 (1.00) RBP4
SCHEMBL25438914 0.88 RBP4 (0.77) RBP4
SCHEMBL24727633 0.87 RBP4 (0.78) RBP4
SCHEMBL29798772 0.87 RBP4 (1.00) RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12364693-B2 Methods of treating metabolic diseases with fused bicyclic pyrazoles BELITE BIO, INC (US) 2025-07-22 US disclosed
EP-4507566-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION Belite Bio, Inc (US) 2025-02-19 EP disclosed
EP-4436577-A1 TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE Belite Bio, Inc (US) 2024-10-02 EP disclosed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 EP disclosed
WO-2023200766-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO, INC (US) 2023-10-19 WO disclosed
WO-2023097221-A1 TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE BELITE BIO, INC (US) 2023-06-01 WO disclosed
WO-2022246238-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC (US) 2022-11-24 WO disclosed
US-20220354844-A1 METHODS OF TREATING METABOLIC DISEASES WITH FUSED BICYCLIC PYRAZOLES BELITE BIO, INC. (KY) 2022-11-10 US disclosed
US-11389444-B2 Methods of treating metabolic diseases with fused bicyclic pyrazoles BELITE BIO, INC (KY) 2022-07-19 US disclosed
EP-3996714-A1 FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE Belite Bio, LLC (US) 2022-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220354844-A1 METHODS OF TREATING METABOLIC DISEASES WITH FUSED BICYCLIC PYRAZOLES RBP4, RBP1, FABP4 RBP4 1/4885
US-12364693-B2 Methods of treating metabolic diseases with fused bicyclic pyrazoles RBP4, RBP1, FABP4 RBP4 1/4885
US-11389444-B2 Methods of treating metabolic diseases with fused bicyclic pyrazoles RBP4, RBP1, FABP4 RBP4 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.