Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701074 | 1.00 | RAB9A (0.41) | RAB9ANPC1CTNNB1WNT3AHTT | |
| Bromide SCHEMBL1984185 | 0.98 | RAB9A (0.41) | RAB9ANPC1CTNNB1WNT3AHTT | |
| SCHEMBL5314559 | 0.86 | CTNNB1 (0.43) | RAB9ANPC1CTNNB1WNT3AHTT | |
| SCHEMBL5312789 | 0.83 | BRD4 (0.43) | RAB9ANPC1CTNNB1WNT3AHTT | |
| SCHEMBL2479225 | 0.81 | CTNNB1 (0.49) | CTNNB1WNT3AKDM4EL3MBTL1NPSR1 | |
| Hydrochloric Acid SCHEMBL1981138 | 0.80 | NOS3 (0.42) | RAB9ANPC1CTNNB1WNT3AHTT | |
| SCHEMBL22756416 | 0.80 | CTNNB1 (0.44) | CTNNB1WNT3AGSK3BKDM4EL3MBTL1 | |
| SCHEMBL2475007 | 0.80 | BRD4 (0.41) | RAB9ANPC1CTNNB1WNT3AHTT | |
| SCHEMBL6110659 | 0.80 | KDM4E (0.46) | GSK3BKDM4EL3MBTL1NPSR1CYP1A2 | |
| SCHEMBL15988698 | 0.79 | CTNNB1 (0.54) | RAB9ANPC1CTNNB1WNT3AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-116547282-A | Heterocyclic compounds and their use for the treatment of helminth infections and diseases | 新基公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |