SCHEMBL29601209

SCHEMBL29601209

C#CCn1cnc2nc(F)nc(F)c21

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22912746 0.76 ADORA2B (0.34) ADORA2B
SCHEMBL22912677 0.71 ADORA2B (0.39) ADORA2B
SCHEMBL22912744 0.62 ADORA2B (0.34) ADORA2B
SCHEMBL22912743 0.59 SLC29A1 (0.43)
SCHEMBL31673230 0.59 ADORA2B (0.42) ADORA2B
SCHEMBL6788435 0.59 NPSR1 (0.42) ADORA2B
SCHEMBL10987026 0.59
SCHEMBL19911438 0.58 QPCT (0.39) ADORA2B
SCHEMBL19911425 0.58 PRPS1 (0.42) ADORA2B
SCHEMBL316930 0.57 ADORA2B (0.62) ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024097262-A1 CHEMOPROTEOMIC CAPTURE OF RNA BINDING ACTIVITY IN LIVING CELLS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2024-05-10 WO claimed
EP-3997089-A1 CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF University Of Virginia Patent Foundation (US) 2022-05-18 EP claimed
WO-2024097262-A1 CHEMOPROTEOMIC CAPTURE OF RNA BINDING ACTIVITY IN LIVING CELLS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2024-05-10 WO disclosed
EP-3997089-A1 CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF University Of Virginia Patent Foundation (US) 2022-05-18 EP disclosed