SCHEMBL29601268

SCHEMBL29601268

OCCOc1c(-c2cccc3ccccc23)cc2ccccc2c1-c1c(OCCO)c(-c2cccc3ccccc23)cc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.45
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA7 P36544 1/20 0.39
KDM4E B2RXH2 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HTR1D P28221 1/20 0.38
HTR1B P28222 1/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 1/20 0.38
MPI P34949 1/20 0.38
SLC6A9 P48067 1/20 0.38
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28713913 0.91 GPR84 (0.40) GPR84CHRNB4CHRNA3CHRNA7KDM4E
SCHEMBL31094274 0.88 CYP11B1 (0.41) GPR84KDM4EMEN1KMT2AALDH1A1
SCHEMBL29506852 0.86 GPR84 (0.48) GPR84KDM4EMEN1KMT2AALDH1A1
SCHEMBL22187663 0.86 GPR84 (0.48) GPR84KDM4EMEN1KMT2AALDH1A1
SCHEMBL30292764 0.86 SLC6A9 (0.43) CHRNB4CHRNA3CHRNA7KDM4EMEN1
SCHEMBL29351066 0.83 HTR1B (0.43) GPR84CHRNB4CHRNA3CHRNA7KDM4E
SCHEMBL11331409 0.83 HTR1B (0.43) GPR84CHRNB4CHRNA3CHRNA7KDM4E
SCHEMBL29601305 0.82 CHRNB4 (0.41) CHRNB4CHRNA3CHRNA7HTR1DHTR1B
SCHEMBL29197310 0.81 CHRNB4 (0.41) CHRNB4CHRNA3CHRNA7KDM4EMEN1
SCHEMBL30971017 0.81 GPR84 (0.49) GPR84KDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113330051-B Thermoplastic resin and optical member 帝人株式会社 2023-04-28 CN disclosed
CN-114375313-A Thermoplastic resin and optical member comprising the same 帝人株式会社 2022-04-19 CN disclosed