Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MAP3K12 | Q12852 | 10/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21031807 | 1.00 | GLA (0.45) | GLAPOLBGAATSHRMTOR | |
| SCHEMBL18072106 | 0.80 | MTOR (0.40) | MTORMAP3K12TNFPIK3CAPIK3CD | |
| SCHEMBL3643010 | 0.80 | ALDH1A1 (0.43) | POLBMTORMAP3K12TNFPIK3CA | |
| SCHEMBL25258979 | 0.78 | GLA (0.42) | GLAPOLBGAATSHRPIK3CD | |
| SCHEMBL909629 | 0.78 | PIK3CD (0.57) | GLAPOLBGAATSHRPIK3CD | |
| SCHEMBL19133107 | 0.78 | GLA (0.42) | GLAPOLBGAATSHRPIK3CD | |
| SCHEMBL30254041 | 0.78 | PIK3CD (0.57) | GLAPOLBGAATSHRPIK3CD | |
| SCHEMBL19349268 | 0.78 | GAA (0.42) | GLAPOLBGAATSHRPIK3CD | |
| SCHEMBL29455898 | 0.78 | GAA (0.42) | GLAPOLBGAATSHRPIK3CD | |
| SCHEMBL11890838 | 0.78 | NOS3 (0.54) | MTORMAP3K12PIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-115746301-A | High-transparency polyimide film containing benzonorbornene structure and preparation method thereof | 慧创(东莞)材料技术有限责任公司 | 2023-03-07 | — | — | CN | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |