SCHEMBL296013

SCHEMBL296013

C[C@H](NN[C@@H](CCCCN)C(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.50
GSR P00390 1/20 0.46
RNPEP Q9H4A4 1/20 0.44
SLC6A5 Q9Y345 1/20 0.43
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
CPB2 Q96IY4 10/20 0.41
GABRR1 P24046 2/20 0.39
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31207031 1.00 FOLH1 (0.50) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL30427337 0.95 FOLH1 (0.44) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL29894486 0.89 FOLH1 (0.59) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL29390540 0.89 FOLH1 (0.59) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL29669470 0.87 FOLH1 (0.58) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL31418390 0.86 FOLH1 (0.47) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL30030191 0.86 FOLH1 (0.47) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL31418389 0.86 FOLH1 (0.47) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL30168351 0.85 FOLH1 (0.50) FOLH1GSRRNPEPSLC6A5MMP2
SCHEMBL28171539 0.84 CPB2 (0.49) FOLH1GSRRNPEPSLC6A5CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 780 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3395373-B1 METHOD FOR LABELLING A BIOLOGICAL TARGETING MOLECULE VIA CONJUGATION WITH A RADIOISOTOPE SUITABLE FOR PET OR SPECT IMAGING GE HEALTHCARE LTD (GB) 2022-10-19 EP claimed
US-10548995-B2 Radiolabelling method GE HEALTHCARE LIMITED (GB) 2020-02-04 US claimed
EP-3036208-B1 RADIOLABELLING METHOD GE HEALTHCARE LTD (GB) 2019-10-02 EP claimed
EP-3083526-B1 PURIFICATION METHOD AND COMPOSITIONS GE HEALTHCARE LTD (GB) 2019-08-07 EP claimed
EP-3237614-B1 NOVEL METHODS FOR DISPLAYING CYCLIC PEPTIDES ON BACTERIOPHAGE PARTICLES LANTHIOPEP BV (NL) 2019-06-26 EP claimed
EP-3395373-A1 METHOD FOR LABELLING A BIOLOGICAL TARGETING MOLECULE VIA CONJUGATION WITH A RADIOISOTOPE SUITABLE FOR PET OR SPECT IMAGING GE Healthcare UK Limited (GB) 2018-10-31 EP claimed
EP-2646060-B1 RADIOCONJUGATION METHOD GE HEALTHCARE LTD (GB) 2018-05-30 EP claimed
US-20170044080-A1 RADIOCONJUGATION METHOD GE HEALTHCARE LIMITED (GB) 2017-02-16 US claimed
US-9493504-B2 Radioconjugation method GE HEALTHCARE LIMITED (GB) 2016-11-15 US claimed
EP-3083526-A1 PURIFICATION METHOD AND COMPOSITIONS GE Healthcare UK Limited (GB) 2016-10-26 EP claimed
WO-2006099026-A2 METHOD AND COMPOSITIONS TO DECREASE SERUM CHOLESTEROL LEVELS GENERAL MILLS, INC. (US) 2006-09-21 WO claimed
US-4501760-A EXTRUDING AN EMULSION OF PROTEIN MICELLES AND VEGATABLE OIL INTO HOT WATER GENERAL FOODS, INC. (CA) 1985-02-26 US claimed
US-4490397-A MIXING STARCH WITH PROTEIN MICELLARS, THEN HOT EXTRUSION GENERAL FOODS INC. (CA) 1984-12-25 US claimed
US-4452782-A IMMUNOPOTENTIATING AGENTS HOFFMANN-LA ROCHE INC. (US) 1984-06-05 US claimed
US-4424151-A Heat gellable protein isolate GENERAL FOODS INC. (CA) 1984-01-03 US claimed
EP-0019072-B1 PENTADECAPEPTIDE, PROCESS FOR THE PREPARATION THEREOF AND IMMUNOPOTENTIATING AGENT F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-09-14 EP claimed
US-4391750-A Heat gellable protein isolate GENERAL FOODS INC. (CA) 1983-07-05 US claimed
US-4285862-A FROM PLANTS GENERAL FOODS, LIMITED (CA) 1981-08-25 US claimed
EP-0019072-A1 Pentadecapeptide, process for the preparation thereof and immunopotentiating agent F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-11-26 EP claimed
US-4035349-A SULFHYDRYL AMINO ACIDS, ESTERS AND AMIDES, VEGETABLE PROTEIN THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-07-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044080-A1 RADIOCONJUGATION METHOD GNRHR, KLK3, DUT FOLH1 12/4885GSR 631/4885RNPEP 159/4885
US-10548995-B2 Radiolabelling method QPCT, ARF5, PAICS FOLH1 116/4885GSR 2446/4885RNPEP 63/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.