Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | PDE2A | O00408 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982228 | 1.00 | LMNA (1.00) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL639000 | 1.00 | LMNA (1.00) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL26030665 | 1.00 | LMNA (1.00) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL638999 | 1.00 | LMNA (1.00) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL10607959 | 1.00 | LMNA (1.00) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL21783540 | 0.89 | LMNA (0.80) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL22289307 | 0.89 | LMNA (0.80) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL24195758 | 0.89 | LMNA (0.80) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL24233653 | 0.89 | LMNA (0.80) | LMNATP53ADORA1ADORA2AADORA3 | |
| SCHEMBL5498071 | 0.89 | LMNA (0.80) | LMNATP53ADORA1ADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |