Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601320 | 0.89 | LMNA (1.00) | LMNATP53HPGDADORA2AADORA2B | |
| SCHEMBL10607959 | 0.89 | LMNA (1.00) | LMNATP53HPGDADORA2AADORA2B | |
| SCHEMBL639000 | 0.89 | LMNA (1.00) | LMNATP53HPGDADORA2AADORA2B | |
| SCHEMBL26030665 | 0.89 | LMNA (1.00) | LMNATP53HPGDADORA2AADORA2B | |
| SCHEMBL638999 | 0.89 | LMNA (1.00) | LMNATP53HPGDADORA2AADORA2B | |
| SCHEMBL23982228 | 0.89 | LMNA (1.00) | LMNATP53HPGDADORA2AADORA2B | |
| SCHEMBL11805362 | 0.89 | LMNA (0.66) | LMNATP53HPGDNT5EHIF1A | |
| SCHEMBL5498071 | 0.88 | LMNA (0.80) | LMNATP53HPGDNT5EHIF1A | |
| SCHEMBL25361191 | 0.87 | LMNA (0.78) | LMNATP53HPGDNT5EHIF1A | |
| SCHEMBL7100664 | 0.87 | LMNA (0.78) | LMNATP53HPGDNT5EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051881-A1 | SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |