Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.30 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410314 | 0.84 | KDM4E (0.36) | — | |
| SCHEMBL6430077 | 0.75 | ABCC4 (0.39) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL13347365 | 0.75 | ABCC4 (0.39) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL27797254 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL27438804 | 0.71 | GPR84 (0.49) | — | |
| SCHEMBL8529276 | 0.71 | SLC22A6 (0.48) | — | |
| SCHEMBL6157808 | 0.71 | SLC22A6 (0.48) | — | |
| SCHEMBL9328721 | 0.71 | SLC22A6 (0.48) | — | |
| SCHEMBL19285469 | 0.71 | CA1 (0.40) | — | |
| SCHEMBL23671019 | 0.71 | CA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4004004-A1 | ARGINASE INHIBITORS AND METHODS OF USE THEREOF | AstraZeneca AB (SE) | 2022-06-01 | — | — | EP | disclosed |