Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | CTSS | P25774 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131636 | 0.89 | MEN1 (0.42) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL31072227 | 0.86 | MEN1 (0.49) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL13906658 | 0.86 | MEN1 (0.49) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL22644797 | 0.82 | MEN1 (0.41) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL4817282 | 0.82 | TDP1 (0.43) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL10309116 | 0.81 | MEN1 (0.45) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL5725026 | 0.80 | MEN1 (0.44) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL5725021 | 0.80 | MEN1 (0.44) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL12896244 | 0.79 | CTSS (0.49) | MEN1GAAKMT2ASYKTDP1 | |
| SCHEMBL21210185 | 0.79 | KMT2A (0.46) | MEN1GAAKMT2ASYKTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4004004-A1 | ARGINASE INHIBITORS AND METHODS OF USE THEREOF | AstraZeneca AB (SE) | 2022-06-01 | — | — | EP | disclosed |