Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.46 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047904 | 1.00 | CTSS (0.49) | CTSSCTSKCTSLCTSBCACNA2D1 | |
| SCHEMBL31072227 | 0.89 | MEN1 (0.49) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL13906658 | 0.89 | MEN1 (0.49) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL14570838 | 0.86 | CTSL (0.45) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL598582 | 0.85 | CACNA2D1 (0.41) | CTSSCTSKCTSLCTSBCACNA2D1 | |
| SCHEMBL4267167 | 0.85 | CACNA2D1 (0.41) | CTSSCTSKCTSLCTSBCACNA2D1 | |
| SCHEMBL4261503 | 0.84 | CACNA2D1 (0.41) | CTSSCTSKCTSLCTSBCACNA2D1 | |
| SCHEMBL4258214 | 0.84 | CACNA2D1 (0.41) | CTSSCTSKCTSLCTSBCACNA2D1 | |
| SCHEMBL599577 | 0.84 | CACNA2D1 (0.41) | CTSSCTSKCTSLCTSBCACNA2D1 | |
| SCHEMBL597356 | 0.84 | CACNA2D1 (0.41) | CTSSCTSKCTSLCTSBCACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120131636-A | Twin medicine and composition and application thereof | 江苏海洋大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-120025292-A | Compound with synergistic analgesic effect, pharmaceutical composition, preparation method and application thereof | 江苏海洋大学 | 2025-05-23 | — | — | CN | disclosed |
| CN-116585298-A | Coupling medicine, composition and application thereof | 江苏海洋大学 | 2023-08-15 | — | — | CN | disclosed |
| US-11703514-B2 | Pregabalin immunoassays | ARK DIAGNOSTICS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| CN-115677507-A | Flurbiprofen derivative and application thereof in medicines | 天地恒一制药股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-3761036-A1 | PREGABALIN IMMUNOASSAYS | ARK Diagnostics, Inc. (US) | 2021-01-06 | — | — | EP | disclosed |
| US-20200341016-A1 | Pregabalin Immunoassays | ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT | 2020-10-29 | — | — | US | disclosed |
| EP-3265074-B1 | PREGABALIN IMMUNOASSAYS | ARK DIAGNOSTICS INC (US) | 2020-08-12 | — | — | EP | disclosed |
| US-10690687-B2 | Pregabalin immunoassays | ARK DIAGNOSTICS, INC. (US) | 2020-06-23 | — | — | US | disclosed |
| US-9958464-B2 | Pregabalin immunoassays | ARK DIAGNOSTICS, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-9422230-B2 | Process for the preparation of an anticonvulsant agent pregabalin hydrochloride | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-08-23 | — | — | US | disclosed |
| US-20160122289-A1 | PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-05 | — | — | US | disclosed |
| US-20160122289-A1 | PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-05 | — | — | US | disclosed |
| US-20160122289-A1 | PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-05 | — | — | US | disclosed |
| WO-2012161798-A1 | FATTY ACID GAMMA AMINOBUTYRIC ACID (GABA) CONJUGATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2012-11-29 | — | — | WO | disclosed |
| US-7879906-B2 | 3-Aminomethyl-5-methyl-hexanoic acid 1-ethyloxycarbonyloxy-ethyl ester; epilepsy, depression, anxiety, psychosis, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, panic, pain | ANCHEN LABORATORIES, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7879906-B2 | 3-Aminomethyl-5-methyl-hexanoic acid 1-ethyloxycarbonyloxy-ethyl ester; epilepsy, depression, anxiety, psychosis, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, panic, pain | ANCHEN LABORATORIES, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| WO-2009118580-A2 | GABA ANALOGS, COMPOSITIONS, AND METHODS FOR MANUFACTURING THEREOF | ANCHEN LABORATORIES, INC (US) | 2009-10-01 | — | — | WO | disclosed |
| US-20080125483-A1 | GABA ANALOGS, COMPOSITIONS AND METHODS FOR MANUFACTURING THEREOF | TWI BIOTECHNOLOGY, INC. (TW) | 2008-05-29 | — | — | US | disclosed |
| US-20080125483-A1 | GABA ANALOGS, COMPOSITIONS AND METHODS FOR MANUFACTURING THEREOF | TWI BIOTECHNOLOGY, INC. (TW) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10690687-B2 | Pregabalin immunoassays | GABRG3, GABRG1, GABRB2 | CTSS 4113/4885CTSK 4206/4885CTSL 3122/4885 |
| US-20200341016-A1 | Pregabalin Immunoassays | GABRG3, GABRG1, GABRB2 | CTSS 4113/4885CTSK 4206/4885CTSL 3122/4885 |
| US-20160122289-A1 | PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE | GABRE, GABRG1, GABRB2 | CTSS 3764/4885CTSK 4050/4885CTSL 3484/4885 |
| US-11703514-B2 | Pregabalin immunoassays | GABRG3, GABRG1, GABRB2 | CTSS 4113/4885CTSK 4206/4885CTSL 3122/4885 |
| US-20080125483-A1 | GABA ANALOGS, COMPOSITIONS AND METHODS FOR MANUFACTURING THEREOF | GABRB1, GABRA5, GABRA1 | CTSS 3626/4885CTSK 3171/4885CTSL 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.