Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | NPFFR2 | Q9Y5X5 | 5/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634976 | 0.90 | MAPK8 (0.54) | MAPK8MAPK9MAPK10SLC6A2CALCRL | |
| SCHEMBL29600734 | 0.89 | CALCRL (0.51) | MAPK8MAPK9MAPK10CALCRLREN | |
| SCHEMBL31122250 | 0.81 | CALCRL (0.53) | MAPK8MAPK9MAPK10CALCRLREN | |
| SCHEMBL29505970 | 0.81 | REN (0.53) | MAPK8MAPK9MAPK10CALCRLREN | |
| SCHEMBL38659222 | 0.79 | MAPK8 (0.57) | MAPK8MAPK9MAPK10CALCRLREN | |
| SCHEMBL38657879 | 0.79 | SLC6A2 (0.63) | SLC6A2CALCRLOPRM1OPRD1OPRK1 | |
| SCHEMBL29506880 | 0.78 | CALCRL (0.52) | MAPK8MAPK9MAPK10CALCRLREN | |
| SCHEMBL30004440 | 0.78 | REN (0.53) | MAPK8MAPK9MAPK10SLC6A2REN | |
| SCHEMBL29575473 | 0.78 | REN (0.51) | SLC6A2CALCRLREN | |
| SCHEMBL31500490 | 0.78 | REN (0.53) | SLC6A2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997103-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2022-05-18 | — | — | EP | disclosed |