Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.51 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.48 |
| ▸ | CTSC | P53634 | 2/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31122250 | 0.92 | CALCRL (0.53) | CALCRLCDYL2CDYLCTSCREN | |
| SCHEMBL29601430 | 0.89 | MAPK8 (0.46) | CALCRLCDYL2CDYLRENMAPK8 | |
| SCHEMBL29506880 | 0.88 | CALCRL (0.52) | CALCRLCDYL2CDYLCTSCREN | |
| SCHEMBL29634944 | 0.85 | CALCRL (0.54) | CALCRLCTSCRENMAPK8MAPK9 | |
| SCHEMBL31071032 | 0.85 | CALCRL (0.55) | CALCRLCDYL2CDYLCTSCREN | |
| SCHEMBL31122251 | 0.83 | CALCRL (0.52) | CALCRLCTSCRENKEAP1MAPK8 | |
| SCHEMBL29634982 | 0.83 | PSMB5 (0.48) | CDYL2CDYLPSMB5STAT3BACE1 | |
| SCHEMBL30123252 | 0.82 | CTSC (0.59) | CALCRLCTSCRENBACE1 | |
| SCHEMBL38657878 | 0.82 | CALCRL (0.43) | CALCRLCTSCRENKEAP1MAPK8 | |
| SCHEMBL29634931 | 0.81 | CALCRL (0.53) | CALCRLCTSCRENKEAP1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997104-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2022-05-18 | — | — | EP | claimed |
| EP-3997103-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2022-05-18 | — | — | EP | claimed |