Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12924130 | 1.00 | EGLN1 (0.59) | EGLN1ALDH1A1HPGDCYP1A2POLB | |
| SCHEMBL12923841 | 0.88 | KDM4E (0.53) | EGLN1ALDH1A1HPGDCYP1A2POLB | |
| SCHEMBL12924825 | 0.87 | HPGDS (0.56) | EGLN1ALDH1A1HPGDCYP1A2POLB | |
| SCHEMBL12925136 | 0.84 | HPGDS (0.53) | ALDH1A1HPGDCYP1A2POLBCYP3A4 | |
| SCHEMBL12896108 | 0.84 | EGLN1 (0.57) | EGLN1HPGDPOLBATMRAB9A | |
| SCHEMBL12923703 | 0.83 | PDE10A (0.53) | ALDH1A1HPGDCYP1A2POLBCYP3A4 | |
| SCHEMBL29601352 | 0.83 | SMN1; SMN2 (0.57) | EGLN1ALDH1A1HPGDCYP1A2POLB | |
| SCHEMBL31086435 | 0.83 | MAPT (0.53) | EGLN1ALDH1A1HPGDCYP1A2POLB | |
| SCHEMBL27039815 | 0.83 | SMN1; SMN2 (0.57) | EGLN1ALDH1A1HPGDCYP1A2POLB | |
| SCHEMBL25362883 | 0.82 | EGLN1 (0.62) | EGLN1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024206939-A2 | SARS-COV-2 ENTRY INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-03 | — | — | WO | disclosed |
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |