Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27039815 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL12923841 | 0.89 | KDM4E (0.53) | RAB9AALDH1A1HPGDPOLBCYP1A2 | |
| SCHEMBL31086435 | 0.84 | MAPT (0.53) | RAB9AALDH1A1HPGDPOLBCYP1A2 | |
| SCHEMBL31086536 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL29601724 | 0.83 | EGLN1 (0.59) | SMN1; SMN2RAB9AALDH1A1HPGDPOLB | |
| SCHEMBL12924130 | 0.83 | EGLN1 (0.59) | SMN1; SMN2RAB9AALDH1A1HPGDPOLB | |
| SCHEMBL12925136 | 0.83 | HPGDS (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL12924825 | 0.82 | HPGDS (0.56) | RAB9AALDH1A1HPGDPOLBCYP1A2 | |
| SCHEMBL31086414 | 0.81 | HPGD (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL29601227 | 0.79 | GRM5 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |