SCHEMBL29601790

SCHEMBL29601790

CC[C@H](Oc1cc(F)c(Cl)cc1C(F)(F)CC)C(=O)OC

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
MKNK2 Q9HBH9 1/20 0.32
MAPT P10636 2/20 0.31
TSHR P16473 1/20 0.31
SCN9A Q15858 2/20 0.31
DHODH Q02127 1/20 0.31
HPGD P15428 2/20 0.30
ALDH1A1 P00352 1/20 0.30
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
PPARG P37231 3/20 0.30
PPARA Q07869 3/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22823984 1.00 GAA (0.33) GAAPOLBMAPK1MKNK2MAPT
SCHEMBL29365366 0.88 PPARG (0.38) GAAPOLBPPARGPPARASMN1; SMN2
SCHEMBL22823983 0.88 PPARG (0.38) GAAPOLBPPARGPPARASMN1; SMN2
SCHEMBL28687049 0.88 PPARG (0.38) GAAPOLBPPARGPPARASMN1; SMN2
SCHEMBL29602077 0.86 AAK1 (0.34) MKNK2MAPT
SCHEMBL22823750 0.86 AAK1 (0.34) MKNK2MAPT
SCHEMBL22823973 0.82 PPARG (0.38) PPARGPPARA
SCHEMBL22823920 0.82 PPOX (0.39) GAAPOLBMAPK1MAPTTSHR
SCHEMBL28676544 0.82 PPARG (0.38) PPARGPPARA
SCHEMBL29367873 0.82 PPARG (0.38) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415771-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2025-09-16 US disclosed
CN-114008012-B Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2025-02-25 CN disclosed
EP-3986852-B1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-10-16 EP disclosed
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2022-12-08 US disclosed
EP-3986852-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2022-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS RYR1, CACNB1, SMN1; SMN2 GAA 2442/4885POLB 4142/4885MAPK1 2692/4885
US-12415771-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, SMN1; SMN2 GAA 2442/4885POLB 4142/4885MAPK1 2692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.