Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336101 | 1.00 | ENPP3 (0.43) | ENPP3ENPP1HTTKMT2AALDH1A1 | |
| Bromide SCHEMBL28204049 | 0.98 | ENPP3 (0.42) | ENPP3ENPP1HTTKMT2AALDH1A1 | |
| Thiophene SCHEMBL22610138 | 0.89 | ENPP1 (0.37) | ENPP3ENPP1HTTKMT2AALDH1A1 | |
| SCHEMBL18397039 | 0.83 | GRM4 (0.35) | ENPP3ENPP1HTTKMT2AALDH1A1 | |
| SCHEMBL17260261 | 0.83 | GRM4 (0.35) | ENPP3ENPP1HTTKMT2AALDH1A1 | |
| SCHEMBL31068961 | 0.83 | GRM4 (0.35) | ENPP3ENPP1HTTKMT2AALDH1A1 | |
| SCHEMBL14333347 | 0.77 | AXL (0.35) | HTTKMT2AALDH1A1HSP90AA1TDP1 | |
| SCHEMBL12203098 | 0.77 | AXL (0.35) | HTTKMT2AALDH1A1HSP90AA1TDP1 | |
| SCHEMBL20640057 | 0.77 | TRPM8 (0.37) | HTTALDH1A1HDAC6HSD17B10PDK2 | |
| SCHEMBL24689311 | 0.75 | AXL (0.35) | HTTKMT2AALDH1A1HSP90AA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087373-A1 | METHODS OF MAKING NICOTINIC ACID DERIVATIVES | VERTELLUS HOLDINGS LLC (US) | 2022-04-28 | — | — | WO | disclosed |