SCHEMBL29602001

SCHEMBL29602001

C=Cc1cc(C(F)(F)CC)c(O[C@@H](C)C(=O)OC)cc1F

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F9 P00740 1/20 0.34
PLAU P00749 1/20 0.34
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24775126 1.00 F9 (0.34) F9PLAUPOLBSMN1; SMN2
SCHEMBL28678027 0.88 PTGDR2 (0.34)
SCHEMBL28678025 0.88 PTGDR2 (0.34)
Ammonia Solution, Strong SCHEMBL28676559 0.87 PTGDR2 (0.34)
SCHEMBL29601786 0.87 F9 (0.39) F9PLAUPOLBSMN1; SMN2
SCHEMBL22823852 0.87 F9 (0.39) F9PLAUPOLBSMN1; SMN2
SCHEMBL29602064 0.82 AAK1 (0.37) F9PLAUPOLBSMN1; SMN2
SCHEMBL22823913 0.82 AAK1 (0.37) F9PLAUPOLBSMN1; SMN2
SCHEMBL22823911 0.81 TAS1R3 (0.38) F9PLAUPOLBSMN1; SMN2
SCHEMBL29601840 0.81 TAS1R3 (0.38) F9PLAUPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415771-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2025-09-16 US disclosed
EP-3986852-B1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-10-16 EP disclosed
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2022-12-08 US disclosed
EP-3986852-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2022-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS RYR1, CACNB1, SMN1; SMN2 F9 4558/4885PLAU 4540/4885POLB 4142/4885
US-12415771-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, SMN1; SMN2 F9 4558/4885PLAU 4540/4885POLB 4142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.