Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.43 |
| ▸ | GABRP | O00591 | 6/20 | 0.43 |
| ▸ | GABRD | O14764 | 6/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.43 |
| ▸ | GABRE | P78334 | 6/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019601 | 0.86 | CYP1A2 (0.59) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL1644358 | 0.83 | POLB (0.46) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL30445565 | 0.83 | POLB (0.46) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL13635198 | 0.83 | POLB (0.46) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL12184767 | 0.83 | POLB (0.46) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL27594663 | 0.81 | LMNA (0.44) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL9127944 | 0.80 | LMNA (0.43) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL30986210 | 0.79 | SIRT6 (0.52) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL7999648 | 0.79 | SIRT6 (0.52) | POLBLMNACYP1A2GABRA1GABRG2 | |
| SCHEMBL1644521 | 0.79 | POLB (0.70) | POLBLMNACYP1A2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |