Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.36 |
| ▸ | LPL | P06858 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 5/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27129530 | 1.00 | GRIN1 (0.41) | GRIN1GRIN2ALIPGLPLBACE1 | |
| SCHEMBL26969389 | 1.00 | GRIN1 (0.41) | GRIN1GRIN2ALIPGLPLBACE1 | |
| SCHEMBL26644198 | 0.93 | GRIN1 (0.38) | GRIN1GRIN2ALIPGLPLBACE1 | |
| SCHEMBL26644195 | 0.93 | GRIN1 (0.38) | GRIN1GRIN2ALIPGLPLBACE1 | |
| SCHEMBL29605611 | 0.93 | GRIN1 (0.38) | GRIN1GRIN2ALIPGLPLBACE1 | |
| SCHEMBL29605511 | 0.79 | GRIN1 (0.47) | GRIN1GRIN2ABACE1HSD11B1ALDH1A1 | |
| SCHEMBL29604868 | 0.79 | GRIN1 (0.47) | GRIN1GRIN2ABACE1HSD11B1ALDH1A1 | |
| SCHEMBL29604635 | 0.77 | LIPG (0.35) | LIPGLPLBACE1ROCK1OPRD1 | |
| SCHEMBL27121386 | 0.77 | LIPG (0.35) | LIPGLPLBACE1ROCK1OPRD1 | |
| SCHEMBL26969399 | 0.77 | LIPG (0.35) | LIPGLPLBACE1ROCK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4244224-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2023-09-20 | — | — | EP | disclosed |
| WO-2022104348-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2022-05-19 | — | — | WO | disclosed |