Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19320362 | 0.83 | PTGDR2 (0.45) | PTGDR2GAAPKML3MBTL1ALDH3A1 | |
| SCHEMBL29604855 | 0.81 | PTGDR2 (0.63) | PTGDR2L3MBTL1LATS1 | |
| SCHEMBL20576441 | 0.81 | PTGDR2 (0.63) | PTGDR2L3MBTL1LATS1 | |
| SCHEMBL7513541 | 0.78 | PTGDR2 (0.43) | PTGDR2GAAPKML3MBTL1ALDH3A1 | |
| SCHEMBL26969367 | 0.78 | LMNA (0.43) | PTGDR2GAAPKML3MBTL1ALDH3A1 | |
| SCHEMBL26969411 | 0.76 | PTGDR2 (0.40) | PTGDR2GAAPKML3MBTL1ALDH3A1 | |
| SCHEMBL29605720 | 0.76 | PTGDR2 (0.42) | PTGDR2PKML3MBTL1POLBLMNA | |
| SCHEMBL3500448 | 0.76 | CA1 (0.49) | PTGDR2GAAPKML3MBTL1ALDH3A1 | |
| SCHEMBL29605488 | 0.76 | CA1 (0.49) | PTGDR2GAAPKML3MBTL1ALDH3A1 | |
| SCHEMBL26969492 | 0.74 | ALDH3A1 (0.44) | PTGDR2GAAPKML3MBTL1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4244224-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2023-09-20 | — | — | EP | disclosed |
| WO-2022104348-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2022-05-19 | — | — | WO | disclosed |