Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358287 | 0.81 | CYP4F2 (0.59) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL7785924 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TDP1ADAMTS4NPC1RAB9A | |
| SCHEMBL1408350 | 0.78 | KMT2A (0.59) | ALDH1A1TDP1NPC1RAB9AHPGD | |
| SCHEMBL5204961 | 0.78 | L3MBTL1 (0.51) | ALDH1A1TDP1NPC1RAB9AHPGD | |
| SCHEMBL5651714 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TDP1ADAMTS4MAPTMEN1 | |
| SCHEMBL27549013 | 0.78 | CYP4F2 (0.56) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL17468329 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TDP1ADAMTS4HPGDMAPT | |
| SCHEMBL9589260 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TDP1ADAMTS4NPC1RAB9A | |
| SCHEMBL19068065 | 0.77 | CYP4F2 (0.54) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL5109307 | 0.77 | KDM4E (0.58) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103149-A1 | NOVEL CARBAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 큐라클 | 2022-05-19 | — | — | WO | disclosed |