Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1924800 | 0.78 | AXL (0.37) | — | |
| SCHEMBL29604834 | 0.78 | AXL (0.37) | — | |
| SCHEMBL24440734 | 0.73 | MAPK1 (0.49) | MAPK1 | |
| SCHEMBL6358084 | 0.73 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL586988 | 0.66 | CYP19A1 (0.34) | — | |
| SCHEMBL14906033 | 0.66 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL19801401 | 0.63 | GRM4 (0.33) | MAPK1 | |
| SCHEMBL29471933 | 0.61 | ADORA2A (0.43) | — | |
| SCHEMBL22583027 | 0.61 | CYP2A6 (0.41) | — | |
| SCHEMBL29435604 | 0.61 | CYP2A6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4244224-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2023-09-20 | — | — | EP | disclosed |
| WO-2022104348-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2022-05-19 | — | — | WO | disclosed |