Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358084 | 0.75 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL14763598 | 0.71 | DYRK1A (0.38) | MAPK1 | |
| SCHEMBL3950985 | 0.71 | PDPK1 (0.38) | MAPK1 | |
| SCHEMBL30180924 | 0.71 | DYRK1A (0.38) | MAPK1 | |
| SCHEMBL30316980 | 0.71 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL30876173 | 0.71 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL24283777 | 0.69 | GRM4 (0.31) | — | |
| SCHEMBL30424529 | 0.69 | GRM4 (0.31) | — | |
| SCHEMBL19801401 | 0.68 | GRM4 (0.33) | MAPK1 | |
| SCHEMBL19258970 | 0.68 | YTHDC1 (0.40) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-112351780-B | Substituted heterocyclic inhibitors of PTPN11 | 纳维尔制药有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-112351780-A | Substituted heterocyclic inhibitors of PTPN11 | 纳维尔制药有限公司 | 2021-02-09 | — | — | CN | disclosed |
| WO-2013063100-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2013060029-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK SHARP & DOHME CORP (US) | 2013-05-02 | — | — | WO | disclosed |