SCHEMBL2960602

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17777979	0.81	KMT2A (0.57)	PDE7ASLC6A4MAPTKDM4EL3MBTL1
	SCHEMBL2961391	0.79	SLC6A4 (0.52)	PDE7ASLC6A2SLC6A4SLC6A3MAPT
	SCHEMBL4706984	0.79	SLC6A2 (0.64)	PDE7ASLC6A2SLC6A4SLC6A3MAPT
	SCHEMBL810531	0.79	MAPT (0.56)	PDE7ASLC6A2SLC6A4SLC6A3MAPT
	SCHEMBL2963623	0.78	MAPT (0.54)	PDE7ASLC6A2SLC6A4SLC6A3MAPT
	SCHEMBL2969105	0.78	SLC6A2 (0.52)	SLC6A2SLC6A4SLC6A3MAPTNPSR1
	SCHEMBL1645181	0.78	SLC6A4 (0.75)	SLC6A2SLC6A4SLC6A3MAPTKDM4E
	SCHEMBL1532370	0.78	MAPT (0.66)	MAPTNPSR1POLBKCNMA1HTT
	SCHEMBL1645802	0.78	SLC6A4 (1.00)	SLC6A2SLC6A4SLC6A3MAPTKDM4E
	SCHEMBL10431594	0.78	ALDH1A1 (0.59)	PDE7AMAPTKDM4EPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.